1347750-82-6
1347750-82-6 structure
- Name: Thiol-PEG3-acid
- Chemical Name: 3-{2-[2-(2-Sulfanylethoxy)ethoxy]ethoxy}propanoic acid
- CAS Number: 1347750-82-6
- Molecular Formula: C9H18O5S
- Molecular Weight: 238.301
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-02 21:24:54
- Modify Date: 2024-01-10 14:09:56
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Thiol-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 3-{2-[2-(2-Sulfanylethoxy)ethoxy]ethoxy}propanoic acid |
|---|---|
| Synonyms |
3-{2-[2-(2-Sulfanylethoxy)ethoxy]ethoxy}propanoic acid
MFCD25424073 Propanoic acid, 3-[2-[2-(2-mercaptoethoxy)ethoxy]ethoxy]- |
| Description | Thiol-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 377.5±37.0 °C at 760 mmHg |
| Molecular Formula | C9H18O5S |
| Molecular Weight | 238.301 |
| Flash Point | 182.1±26.5 °C |
| Exact Mass | 238.087494 |
| LogP | -0.30 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.482 |