20299-15-4

20299-15-4 structure

Name: 5-methoxycarbonylmethyl-2-thiouridine
Chemical Name: 5-methoxycarbonylmethyl-2-thiouridine
CAS Number: 20299-15-4
Molecular Formula: C₁₂H₁₆N₂O₇S
Molecular Weight: 332.33
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-06-19 05:51:38
Modify Date: 2024-01-17 21:03:05
5-Methoxycarbonylmethyl-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5-methoxycarbonylmethyl-2-thiouridine
Synonyms	4(1H)-Pyrimidinone, 2,3-dihydro-5-(2-methoxy-2-oxoethyl)-1-β-D-ribofuranosyl-2-thioxo- 5-methoxycarbonylmethyl-2-thiouridine 5-(2-Methoxy-2-oxoethyl)-1-(β-D-ribofuranosyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone

Description	5-Methoxycarbonylmethyl-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.