39483-48-2

39483-48-2 structure

Name: 5’-Azido-5’-deoxyuridine
Chemical Name: 1-(5-Azido-5-deoxy-β-D-ribofuranosyl)-4-hydroxy-2(1H)-pyrimidinone
CAS Number: 39483-48-2
Molecular Formula: C₉H₁₁N₅O₅
Molecular Weight: 269.21
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-06-15 20:51:19
Modify Date: 2024-09-07 13:11:02
5’-Azido-5’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-(5-Azido-5-deoxy-β-D-ribofuranosyl)-4-hydroxy-2(1H)-pyrimidinone
Synonyms	1-(5-Azido-5-deoxy-β-D-ribofuranosyl)-4-hydroxy-2(1H)-pyrimidinone 2(1H)-Pyrimidinone, 1-(5-azido-5-deoxy-β-D-ribofuranosyl)-4-hydroxy-

Description	5’-Azido-5’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.