1612192-00-3

1612192-00-3 structure

Name: 2-Chloro-6-(furan-2-yl) purine-beta-D-(3’-deoxy-3’-fluoro)-riboside
Chemical Name: 2-Chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(2-furyl)-9H-purine
CAS Number: 1612192-00-3
Molecular Formula: C₁₄H₁₂ClFN₄O₄
Molecular Weight: 354.72
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-07-02 00:11:06
Modify Date: 2024-01-11 15:52:27
2-Chloro-6-(furan-2-yl) purine-beta-D-(3’-deoxy-3’-fluoro)-riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-Chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(2-furyl)-9H-purine
Synonyms	9H-Purine, 2-chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(2-furanyl)- 2-Chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(2-furyl)-9H-purine

Description	2-Chloro-6-(furan-2-yl) purine-beta-D-(3’-deoxy-3’-fluoro)-riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.