Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

1462267-08-8

1462267-08-8 structure

Name: CID-46943215
Chemical Name: 2-{2-[(4-Bromophenyl)amino]-2-oxoethoxy}-N-{2-[methyl(phenyl)amino]-2-oxoethyl}benzamide
CAS Number: 1462267-08-8
Molecular Formula: C₂₄H₂₂BrN₃O₄
Molecular Weight: 496.35
Catalog: Research Areas Others
Create Date: 2018-06-14 02:15:21
Modify Date: 2024-02-28 18:36:27
ML266 is glucocerebrosidase (GCase) molecule chaperone with IC50 of 2.5 µM. ML266 binds to GCase and transports of the mutant protein to the lysosome, and resume the activity of GCase. ML266 dose not inhibit the GCase enzyme’s action. ML266 has the potential for the research of gaucher disease[1].

Name	2-{2-[(4-Bromophenyl)amino]-2-oxoethoxy}-N-{2-[methyl(phenyl)amino]-2-oxoethyl}benzamide
Synonyms	Benzamide, 2-[2-[(4-bromophenyl)amino]-2-oxoethoxy]-N-[2-(methylphenylamino)-2-oxoethyl]- 2-{2-[(4-Bromophenyl)amino]-2-oxoethoxy}-N-{2-[methyl(phenyl)amino]-2-oxoethyl}benzamide CID-46943215

Description	ML266 is glucocerebrosidase (GCase) molecule chaperone with IC50 of 2.5 µM. ML266 binds to GCase and transports of the mutant protein to the lysosome, and resume the activity of GCase. ML266 dose not inhibit the GCase enzyme’s action. ML266 has the potential for the research of gaucher disease[1].
Related Catalog	Research Areas >> Others
References	[1]. Rogers S, et al. Discovery, SAR, and Biological Evaluation of Non-inhibitory Chaperones of Glucocerebrosidase. 2012 Mar 27 [updated 2013 Mar 7].