159001-25-9
159001-25-9 structure
- Name: Dihydrocephalomannine
- Chemical Name: (2α,5β,7β,10β,13α)-4,10-Diacetoxy-1,7-dihydroxy-13-({(2R,3S)-2-hydroxy-3-[(2-methylbutanoyl)amino]-3-phenylpropanoyl}oxy)-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
- CAS Number: 159001-25-9
- Molecular Formula: C45H55NO14
- Molecular Weight: 833.917
- Catalog: Research Areas Cancer
- Create Date: 2018-06-27 00:01:45
- Modify Date: 2024-06-27 20:10:07
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Dihydrocephalomannine (compound 1b), an analogue of Paclitaxel, shows reduced cytotoxicity and tubulin binding compared to Paclitaxel[1].
| Name | (2α,5β,7β,10β,13α)-4,10-Diacetoxy-1,7-dihydroxy-13-({(2R,3S)-2-hydroxy-3-[(2-methylbutanoyl)amino]-3-phenylpropanoyl}oxy)-9-oxo-5,20-epoxytax-11-en-2-yl benzoate |
|---|---|
| Synonyms |
benzenepropanoic acid, α-hydroxy-β-[(2-methyl-1-oxobutyl)amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
(2α,5β,7β,10β,13α)-4,10-Diacetoxy-1,7-dihydroxy-13-({(2R,3S)-2-hydroxy-3-[(2-methylbutanoyl)amino]-3-phenylpropanoyl}oxy)-9-oxo-5,20-epoxytax-11-en-2-yl benzoate |
| Description | Dihydrocephalomannine (compound 1b), an analogue of Paclitaxel, shows reduced cytotoxicity and tubulin binding compared to Paclitaxel[1]. |
|---|---|
| Related Catalog | |
| References |
[1]. Paclitaxel Analogue |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 922.6±65.0 °C at 760 mmHg |
| Molecular Formula | C45H55NO14 |
| Molecular Weight | 833.917 |
| Flash Point | 511.8±34.3 °C |
| Exact Mass | 833.362244 |
| LogP | 6.50 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.606 |