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1621616-14-5

1621616-14-5 structure
1621616-14-5 structure
  • Name: Methylamino-PEG4-Boc
  • Chemical Name: 2-Methyl-2-propanyl 5,8,11,14-tetraoxa-2-azaheptadecan-17-oate
  • CAS Number: 1621616-14-5
  • Molecular Formula: C16H33NO6
  • Molecular Weight: 335.436
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-27 05:17:52
  • Modify Date: 2024-01-10 09:05:12
  • Methylamino-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-Methyl-2-propanyl 5,8,11,14-tetraoxa-2-azaheptadecan-17-oate
Synonyms 5,8,11,14-Tetraoxa-2-azaheptadecan-17-oic acid, 1,1-dimethylethyl ester
2-Methyl-2-propanyl 5,8,11,14-tetraoxa-2-azaheptadecan-17-oate
MFCD28155210
Description Methylamino-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.0±0.1 g/cm3
Boiling Point 401.7±35.0 °C at 760 mmHg
Molecular Formula C16H33NO6
Molecular Weight 335.436
Flash Point 196.8±25.9 °C
Exact Mass 335.230774
LogP 0.08
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.448