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  • DC Chemicals Limited
  • China
  • Product Name: AZD5153
  • Price: $750.0/100mg $1300.0/250mg $2700.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

1869912-39-9

1869912-39-9 structure
1869912-39-9 structure
  • Name: AZD-5153
  • Chemical Name: C7C7U6YEAO
  • CAS Number: 1869912-39-9
  • Molecular Formula: C25H33N7O3
  • Molecular Weight: 479.57
  • Catalog: Research Areas Cancer
  • Create Date: 2018-06-19 14:49:45
  • Modify Date: 2024-01-19 23:53:26
  • AZD5153 (Compound 13) is a trivalent triazolpyrazine bromide domain (BRD), bromodomain andextraterminal (BET) inhibitor. AZD5153 has down-regulated c-Myc gene and tumor growth inhibition activity. AZD5153 can be used in the study of BET small molecule inhibitors [1].

Name C7C7U6YEAO
Synonyms 2-Piperazinone, 4-[2-[4-[1-(3-methoxy-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-4-piperidinyl]phenoxy]ethyl]-1,3-dimethyl-, (3R)-
C7C7U6YEAO
(3R)-4-(2-{4-[1-(3-Methoxy[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-4-piperidinyl]phenoxy}ethyl)-1,3-dimethyl-2-piperazinone
(3~{r})-4-[2-[4-[1-(3-Methoxy-[1,2,4]triazolo[4,3-B]pyridazin-6-Yl)piperidin-4-Yl]phenoxy]ethyl]-1,3-Dimethyl-Piperazin-2-One
MFCD30530420
AZD-5153
CPD1544
Description AZD5153 (Compound 13) is a trivalent triazolpyrazine bromide domain (BRD), bromodomain andextraterminal (BET) inhibitor. AZD5153 has down-regulated c-Myc gene and tumor growth inhibition activity. AZD5153 can be used in the study of BET small molecule inhibitors [1].
Related Catalog
References

[1]. Bradbury RH, et al. Optimization of a Series of Bivalent Triazolopyridazine Based Bromodomain and Extraterminal Inhibitors: The Discovery of (3R)-4-[2-[4-[1-(3-Methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-4-piperidyl]phenoxy]ethyl]-1,3-dimethyl-piperazin-2-one (AZD5153). J Med Chem. 2016 Sep 8;59(17):7801-17.  

Density 1.3±0.1 g/cm3
Molecular Formula C25H33N7O3
Molecular Weight 479.57
Exact Mass 479.264496
LogP 2.32
Index of Refraction 1.668