263701-23-1

263701-23-1 structure

Name: (1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol
Chemical Name: 21A41Y02XF
CAS Number: 263701-23-1
Molecular Formula: C₁₁H₁₂F₂O₄
Molecular Weight: 246.21
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-06-28 08:40:55
Modify Date: 2024-01-17 10:39:36
(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	21A41Y02XF
Synonyms	1-deoxy-1-(2,4-difluorophenyl)--D-ribofuranose 21A41Y02XF D-Ribitol, 1,4-anhydro-1-C-(2,4-difluorophenyl)-, (1S)- (1S)-1,4-Anhydro-1-(2,4-difluorophenyl)-D-ribitol

Description	(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.