37805-89-3

37805-89-3 structure

Name: 5-Methoxy-4-thiouridine
Chemical Name: 5-Methoxy-1-(β-D-ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
CAS Number: 37805-89-3
Molecular Formula: C₁₀H₁₄N₂O₆S
Molecular Weight: 290.29
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-06-23 13:54:22
Modify Date: 2024-01-11 20:07:27
5-Methoxy-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5-Methoxy-1-(β-D-ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
Synonyms	5-Methoxy-1-(β-D-ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone 2(1H)-Pyrimidinone, 3,4-dihydro-5-methoxy-1-β-D-ribofuranosyl-4-thioxo-

Description	5-Methoxy-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.