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4051-59-6

4051-59-6 structure
4051-59-6 structure
  • Name: MSX-130
  • Chemical Name: 2,2'-(1,4-Phenylene)bis(4,5-diphenyl-1H-imidazole)
  • CAS Number: 4051-59-6
  • Molecular Formula: C36H26N4
  • Molecular Weight: 514.618
  • Catalog: Signaling Pathways GPCR/G Protein CXCR
  • Create Date: 2018-06-13 07:55:01
  • Modify Date: 2025-08-26 22:55:27
  • MSX-130 is a CXCR4 antagonist. MSX-130 inhibits cancer metastasis[1].

Name 2,2'-(1,4-Phenylene)bis(4,5-diphenyl-1H-imidazole)
Synonyms 2,2'-(1,4-Phenylene)bis(4,5-diphenyl-1H-imidazole)
2,2'-benzene-1,4-diylbis(4,5-diphenyl-1H-imidazole)
1H-Imidazole, 2,2'-(1,4-phenylene)bis[4,5-diphenyl-
Description MSX-130 is a CXCR4 antagonist. MSX-130 inhibits cancer metastasis[1].
Related Catalog
Target

CXCR4

In Vitro The C-X-C chemokine receptor-4 (CXCR4) is a seven trans-membrane G-protein coupled receptor (GPCR) classified as a member of the family I GPCR or rhodopsin-like GPCR family. CXCR4 plays an important role in cancer metastasis, regulation of stem cell trafficking, and neovascularization[1].
References

[1]. Zhan W, et al. Discovery of small molecule CXCR4 antagonists. J Med Chem. 2007 Nov 15;50(23):5655-64.

Density 1.2±0.1 g/cm3
Boiling Point 766.3±48.0 °C at 760 mmHg
Molecular Formula C36H26N4
Molecular Weight 514.618
Flash Point 326.5±22.5 °C
Exact Mass 514.215759
LogP 11.84
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.672
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