1062609-96-4

1062609-96-4 structure

Name: (R)-(-)-O-Desmethyl Venlafaxine D6
Chemical Name: 4-[(1R)-2-{Bis[(2H3)methyl]amino}-1-(1-hydroxycyclohexyl)ethyl]phenol
CAS Number: 1062609-96-4
Molecular Formula: C₁₆H₁₉D₆NO₂
Molecular Weight: 269.412
Catalog: Research Areas Neurological Disease
Create Date: 2018-07-16 05:09:57
Modify Date: 2024-01-04 19:59:01
(R)-(-)-O-Desmethyl Venlafaxine D6 is the deuterium labeled (R)-(-)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine (HY-B0196) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].

Name	4-[(1R)-2-{Bis[(2H3)methyl]amino}-1-(1-hydroxycyclohexyl)ethyl]phenol
Synonyms	4-[(1R)-2-{Bis[(2H3)methyl]amino}-1-(1-hydroxycyclohexyl)ethyl]phenol Phenol, 4-[(1R)-2-(dimethyl-d3-amino)-1-(1-hydroxycyclohexyl)ethyl]-

Description	(R)-(-)-O-Desmethyl Venlafaxine D6 is the deuterium labeled (R)-(-)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine (HY-B0196) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Yijin Liu, et al. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. J Chromatogr A. 2015 Nov 13;1420:119-28. [2]. F P Bymaste, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.