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1334169-90-2

1334169-90-2 structure
1334169-90-2 structure
  • Name: m-PEG8-Mal
  • Chemical Name: 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl)propanamide
  • CAS Number: 1334169-90-2
  • Molecular Formula: C24H42N2O11
  • Molecular Weight: 534.597
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-08 23:30:47
  • Modify Date: 2025-08-26 10:47:08
  • m-PEG8-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl)propanamide
Synonyms 1H-Pyrrole-1-propanamide, 2,5-dihydro-N-3,6,9,12,15,18,21,24-octaoxapentacos-1-yl-2,5-dioxo-
3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl)propanamide
Description m-PEG8-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Boiling Point 659.0±55.0 °C at 760 mmHg
Molecular Formula C24H42N2O11
Molecular Weight 534.597
Flash Point 352.3±31.5 °C
Exact Mass 534.278870
LogP -3.50
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.489
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