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1347750-85-9

1347750-85-9 structure
1347750-85-9 structure
  • Name: Hydroxy-PEG6-acid
  • Chemical Name: 1-Hydroxy-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid
  • CAS Number: 1347750-85-9
  • Molecular Formula: C15H30O9
  • Molecular Weight: 354.393
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-24 00:04:21
  • Modify Date: 2024-01-05 18:48:15
  • Hydroxy-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 1-Hydroxy-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid
Synonyms 3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-hydroxy-
1-Hydroxy-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid
Description Hydroxy-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.2±0.1 g/cm3
Boiling Point 489.6±45.0 °C at 760 mmHg
Molecular Formula C15H30O9
Molecular Weight 354.393
Flash Point 168.9±22.2 °C
Exact Mass 354.188995
LogP -2.78
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.468