172605-95-7

172605-95-7 structure

Name: 2’-β-C-Methyl-6-azauridine
Chemical Name: 2-(2-C-Methyl-β-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione
CAS Number: 172605-95-7
Molecular Formula: C₉H₁₃N₃O₆
Molecular Weight: 259.22
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-07-03 09:53:55
Modify Date: 2024-02-04 13:35:39
2’-β-C-Methyl-6-azauridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-(2-C-Methyl-β-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione
Synonyms	1,2,4-Triazine-3,5(2H,4H)-dione, 2-(2-C-methyl-β-D-ribofuranosyl)- 2-(2-C-Methyl-β-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione

Description	2’-β-C-Methyl-6-azauridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.