439579-23-4

439579-23-4 structure

Name: 3’-Deoxy-3’-fluoro-6-azauridine
Chemical Name: 2-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione
CAS Number: 439579-23-4
Molecular Formula: C₈H₁₀FN₃O₅
Molecular Weight: 247.18
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-07-12 08:24:06
Modify Date: 2024-02-02 16:09:05
3’-Deoxy-3’-fluoro-6-azauridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione
Synonyms	1,2,4-Triazine-3,5(2H,4H)-dione, 2-(3-deoxy-3-fluoro-β-D-ribofuranosyl)- 2-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione

Description	3’-Deoxy-3’-fluoro-6-azauridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.