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868594-43-8

868594-43-8 structure
868594-43-8 structure
  • Name: Benzyl-PEG7-amine
  • Chemical Name: 1-Phenyl-2,5,8,11,14,17,20-heptaoxadocosan-22-amine
  • CAS Number: 868594-43-8
  • Molecular Formula: C21H37NO7
  • Molecular Weight: 415.521
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-13 20:43:35
  • Modify Date: 2024-01-09 07:56:51
  • Benzyl-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 1-Phenyl-2,5,8,11,14,17,20-heptaoxadocosan-22-amine
Synonyms 1-Phenyl-2,5,8,11,14,17,20-heptaoxadocosan-22-amine
MFCD29049391
2,5,8,11,14,17,20-Heptaoxadocosan-22-amine, 1-phenyl-
Description Benzyl-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 502.0±45.0 °C at 760 mmHg
Molecular Formula C21H37NO7
Molecular Weight 415.521
Flash Point 251.1±22.4 °C
Exact Mass 415.256989
LogP -0.75
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.492