944560-99-0

944560-99-0 structure

Name: Propargyl-PEG6-alcohol
Chemical Name: 3,6,9,12,15,18-Hexaoxahenicos-20-yn-1-ol
CAS Number: 944560-99-0
Molecular Formula: C₁₅H₂₈O₇
Molecular Weight: 320.379
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-21 23:49:50
Modify Date: 2025-08-25 18:00:06
Propargyl-PEG6-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	3,6,9,12,15,18-Hexaoxahenicos-20-yn-1-ol
Synonyms	3,6,9,12,15,18-Hexaoxahenicos-20-yn-1-ol 3,6,9,12,15,18-Hexaoxaheneicos-20-yn-1-ol

Description	Propargyl-PEG6-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Goswami LN, et al. Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery. Org Biomol Chem. 2013 Feb 21;11(7):1116-26.