118706-49-3

118706-49-3 structure

Name: 2-Iodo-2'-deoxyadenosine
Chemical Name: 2'-Deoxy-2-iodoadenosine
CAS Number: 118706-49-3
Molecular Formula: C₁₀H₁₂IN₅O₃
Molecular Weight: 377.14
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-07-10 11:17:13
Modify Date: 2025-08-26 14:06:52
2′-Deoxy-2-iodoadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2'-Deoxy-2-iodoadenosine
Synonyms	2'-Deoxy-2-iodoadenosine Adenosine, 2'-deoxy-2-iodo-

Description	2′-Deoxy-2-iodoadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.