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1863885-74-8

1863885-74-8 structure
1863885-74-8 structure
  • Name: Fmoc-N-PEG7-acid
  • Chemical Name: 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25-octaoxa-4-azaoctacosan-28-oic acid
  • CAS Number: 1863885-74-8
  • Molecular Formula: C32H45NO11
  • Molecular Weight: 619.700
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-12 07:39:26
  • Modify Date: 2024-01-02 21:35:58
  • Fmoc-N-amido-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25-octaoxa-4-azaoctacosan-28-oic acid
Synonyms 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25-octaoxa-4-azaoctacosan-28-oic acid
2,7,10,13,16,19,22,25-Octaoxa-4-azaoctacosan-28-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
Description Fmoc-N-amido-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Boiling Point 758.0±60.0 °C at 760 mmHg
Molecular Formula C32H45NO11
Molecular Weight 619.700
Flash Point 412.2±32.9 °C
Exact Mass 619.299255
LogP 1.23
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.534