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1334177-78-4

1334177-78-4 structure
1334177-78-4 structure
  • Name: Bis-PEG5-PFP ester
  • Chemical Name: Bis(pentafluorophenyl) 4,7,10,13,16-pentaoxanonadecane-1,19-dioate
  • CAS Number: 1334177-78-4
  • Molecular Formula: C26H24F10O9
  • Molecular Weight: 670.447
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-01 23:52:00
  • Modify Date: 2025-08-27 18:34:05
  • Bis-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bis(pentafluorophenyl) 4,7,10,13,16-pentaoxanonadecane-1,19-dioate
Synonyms 4,7,10,13,16-Pentaoxanonadecane-1,19-dioic acid, bis(2,3,4,5,6-pentafluorophenyl) ester
Bis(pentafluorophenyl) 4,7,10,13,16-pentaoxanonadecane-1,19-dioate
Description Bis-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.4±0.1 g/cm3
Boiling Point 606.0±55.0 °C at 760 mmHg
Molecular Formula C26H24F10O9
Molecular Weight 670.447
Flash Point 308.3±26.4 °C
Exact Mass 670.126038
LogP 3.56
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.464
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