160203-74-7

160203-74-7 structure

Name: 5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine
Chemical Name: [(2S,5R)-5-(5-Fluoro-2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-2,5-dihydro-2-furanyl]methyl acetate
CAS Number: 160203-74-7
Molecular Formula: C₁₁H₁₁FN₂O₅
Molecular Weight: 270.21
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-06-20 08:35:19
Modify Date: 2025-08-27 12:29:16
5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	[(2S,5R)-5-(5-Fluoro-2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-2,5-dihydro-2-furanyl]methyl acetate
Synonyms	[(2S,5R)-5-(5-Fluoro-2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-2,5-dihydro-2-furanyl]methyl acetate 2,4(1H,3H)-Pyrimidinedione, 1-[(2R,5S)-5-[(acetyloxy)methyl]-2,5-dihydro-2-furanyl]-5-fluoro-

Description	5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.