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1807539-07-6

1807539-07-6 structure
1807539-07-6 structure
  • Name: Benzyl-PEG5-Ms
  • Chemical Name: 1-Phenyl-2,5,8,11,14-pentaoxahexadecan-16-yl methanesulfonate
  • CAS Number: 1807539-07-6
  • Molecular Formula: C18H30O8S
  • Molecular Weight: 406.491
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-08 13:58:06
  • Modify Date: 2024-01-10 12:35:49
  • Benzyl-PEG5-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 1-Phenyl-2,5,8,11,14-pentaoxahexadecan-16-yl methanesulfonate
Synonyms MFCD28976666
1-Phenyl-2,5,8,11,14-pentaoxahexadecan-16-yl methanesulfonate
2,5,8,11,14-Pentaoxahexadecan-16-ol, 1-phenyl-, methanesulfonate
Benzyl-PEG5-MS
Description Benzyl-PEG5-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Boiling Point 529.4±50.0 °C at 760 mmHg
Molecular Formula C18H30O8S
Molecular Weight 406.491
Flash Point 274.0±30.1 °C
Exact Mass 406.166138
LogP 0.06
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.498