215181-61-6

215181-61-6 structure

Name: m-PEG2-azide
Chemical Name: 1-Azido-2-(2-methoxyethoxy)ethane
CAS Number: 215181-61-6
Molecular Formula: C₅H₁₁N₃O₂
Molecular Weight: 145.160
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-06 19:34:30
Modify Date: 2024-01-10 17:37:03
m-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Name	1-Azido-2-(2-methoxyethoxy)ethane
Synonyms	Ethane, 1-azido-2-(2-methoxyethoxy)- 1-Azido-2-(2-methoxyethoxy)ethane MFCD19672689 m-PEG2-Azide Ethane, 1-(2-azidoethoxy)-2-methoxy-

Description	m-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.