849590-42-7

849590-42-7 structure

Name: Blepharotriol
Chemical Name: Methyl (2R,4aS,6aS,12bR,14aS,14bR)-9,10,11-trihydroxy-2,4a,6a,12b,14a-pentamethyl-8-oxo-1,2,3,4,4a,5,6,6a,8,12b,13,14,14a,14b-tetradecahydro-2-picenecarboxylate
CAS Number: 849590-42-7
Molecular Formula: C₂₉H₃₈O₆
Molecular Weight: 482.608
Catalog: Research Areas Cancer
Create Date: 2018-06-07 19:59:00
Modify Date: 2025-08-25 20:36:43
Blepharotriol is a phenolic triterpene that can be found in Maytenus blepharodes. Blepharotriol shows antimicrobial activity with a MIC value of 8-4 µg/ml for Bacillus subtilis. Blepharotriol shows cytotoxic activity with IC50s of 12.2, >20, >20 µM for HeLa, Hep-2, Vero cells, respectively[1].

Name	Methyl (2R,4aS,6aS,12bR,14aS,14bR)-9,10,11-trihydroxy-2,4a,6a,12b,14a-pentamethyl-8-oxo-1,2,3,4,4a,5,6,6a,8,12b,13,14,14a,14b-tetradecahydro-2-picenecarboxylate
Synonyms	Methyl (2R,4aS,6aS,12bR,14aS,14bR)-9,10,11-trihydroxy-2,4a,6a,12b,14a-pentamethyl-8-oxo-1,2,3,4,4a,5,6,6a,8,12b,13,14,14a,14b-tetradecahydro-2-picenecarboxylate 2-Picenecarboxylic acid, 1,2,3,4,4a,5,6,6a,8,12b,13,14,14a,14b-tetradecahydro-9,10,11-trihydroxy-2,4a,6a,12b,14a-pentamethyl-8-oxo-, methyl ester, (2R,4aS,6aS,12bR,14aS,14bR)-

Description	Blepharotriol is a phenolic triterpene that can be found in Maytenus blepharodes. Blepharotriol shows antimicrobial activity with a MIC value of 8-4 µg/ml for Bacillus subtilis. Blepharotriol shows cytotoxic activity with IC50s of 12.2, >20, >20 µM for HeLa, Hep-2, Vero cells, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Félix M.Rodríguez, et al. New phenolic triterpenes from Maytenus blepharodes. Semisynthesis of 6-deoxoblepharodol from pristimerin. Tetrahedron. 2005, 61 (9): 2513-2519.