1807537-42-3
1807537-42-3 structure
- Name: Mal-PEG5-NHS ester
- Chemical Name: 1-{18-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-18-oxo-3,6,9,12,15-pentaoxaoctadec-1-yl}-1H-pyrrole-2,5-dione
- CAS Number: 1807537-42-3
- Molecular Formula: C21H30N2O11
- Molecular Weight: 486.470
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-22 12:06:05
- Modify Date: 2024-01-02 18:16:22
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Mal-PEG5-NHS ester is an Alkyl/ether and PEG-based PROTAC linker can be used in the synthesis of PROTACs.
| Name | 1-{18-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-18-oxo-3,6,9,12,15-pentaoxaoctadec-1-yl}-1H-pyrrole-2,5-dione |
|---|---|
| Synonyms |
1-{18-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-18-oxo-3,6,9,12,15-pentaoxaoctadec-1-yl}-1H-pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 1-[18-[(2,5-dioxo-1-pyrrolidinyl)oxy]-18-oxo-3,6,9,12,15-pentaoxaoctadec-1-yl]- |
| Description | Mal-PEG5-NHS ester is an Alkyl/ether and PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 608.4±65.0 °C at 760 mmHg |
| Molecular Formula | C21H30N2O11 |
| Molecular Weight | 486.470 |
| Flash Point | 321.7±34.3 °C |
| Exact Mass | 486.184967 |
| LogP | -3.32 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.541 |
| Storage condition | 2-8°C |