1233234-77-9

1233234-77-9 structure
1233234-77-9 structure
  • Name: Boc-NH-PEG11-NH2
  • Chemical Name: Boc-NH-PEG11-CH2CH2NH2
  • CAS Number: 1233234-77-9
  • Molecular Formula: C29H60N2O13
  • Molecular Weight: 644.792
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-11-10 12:19:54
  • Modify Date: 2024-01-11 08:30:10
  • Boc-NH-PEG11-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-NH-PEG11-CH2CH2NH2
Synonyms Boc-PEG-amine (n=11)
2-Methyl-2-propanyl (35-amino-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacont-1-yl)carbamate
MFCD03453245
Carbamic acid, N-(35-amino-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacont-1-yl)-, 1,1-dimethylethyl ester
Description Boc-NH-PEG11-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 667.6±55.0 °C at 760 mmHg
Molecular Formula C29H60N2O13
Molecular Weight 644.792
Flash Point 357.5±31.5 °C
Exact Mass 644.409546
LogP -3.03
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.467