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1309460-29-4

1309460-29-4 structure
1309460-29-4 structure
  • Name: Acid-PEG5-C2-Boc
  • Chemical Name: Acid-PEG5-t-butyl ester
  • CAS Number: 1309460-29-4
  • Molecular Formula: C18H34O9
  • Molecular Weight: 394.457
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-02 16:24:55
  • Modify Date: 2024-01-09 11:20:01
  • Acid-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Acid-PEG5-t-butyl ester
Synonyms MFCD18916989
2,2-Dimethyl-4-oxo-3,7,10,13,16,19-hexaoxadocosan-22-oic acid
4,7,10,13,16-Pentaoxanonadecane-1,19-dioic acid, mono(1,1-dimethylethyl) ester
Description Acid-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 495.2±45.0 °C at 760 mmHg
Molecular Formula C18H34O9
Molecular Weight 394.457
Flash Point 163.1±22.2 °C
Exact Mass 394.220276
LogP -0.21
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.460