Name | Acid-PEG5-t-butyl ester |
---|---|
Synonyms |
MFCD18916989
2,2-Dimethyl-4-oxo-3,7,10,13,16,19-hexaoxadocosan-22-oic acid 4,7,10,13,16-Pentaoxanonadecane-1,19-dioic acid, mono(1,1-dimethylethyl) ester |
Description | Acid-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
---|---|
Related Catalog | |
Target |
PEGs Alkyl/ether |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.1±0.1 g/cm3 |
---|---|
Boiling Point | 495.2±45.0 °C at 760 mmHg |
Molecular Formula | C18H34O9 |
Molecular Weight | 394.457 |
Flash Point | 163.1±22.2 °C |
Exact Mass | 394.220276 |
LogP | -0.21 |
Vapour Pressure | 0.0±2.7 mmHg at 25°C |
Index of Refraction | 1.460 |