1310827-26-9

1310827-26-9 structure

Name: S-Acetyl-PEG3-azide
Chemical Name: S-Acetyl-PEG3-Azido
CAS Number: 1310827-26-9
Molecular Formula: C₁₀H₁₉N₃O₄S
Molecular Weight: 277.341
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-07 13:27:37
Modify Date: 2024-01-10 13:38:11
S-Acetyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	S-Acetyl-PEG3-Azido
Synonyms	Ethanethioic acid, S-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl] ester S-(2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}ethyl) ethanethioate MFCD22201539

Description	S-Acetyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562