Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Peptide 74
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

132116-39-3

132116-39-3 structure

132116-39-3 structure

Name: Peptide 74
Chemical Name: peptide 74
CAS Number: 132116-39-3
Molecular Formula: C₆₂H₁₀₇N₂₃O₂₀S₂
Molecular Weight: 1558.79
Catalog: Research Areas Cancer
Create Date: 2018-06-16 14:22:11
Modify Date: 2025-08-24 18:52:03
Peptide 74 is a synthetic peptide containing the prodomain sequence of matrix metalloproteinase (MMP). Peptide 74 inhibits the activated form of the 72-kDa type IV collagenase in vitro[1].

Name	peptide 74

Description	Peptide 74 is a synthetic peptide containing the prodomain sequence of matrix metalloproteinase (MMP). Peptide 74 inhibits the activated form of the 72-kDa type IV collagenase in vitro[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Peptide 74 (30 μM) reduces both A2058 and HT 1080 tumor cell invasion by 60-80%[1]. Peptide 74 (30 μM) shows no cytotoxic action and does not inhibit chemotaxis or affect HT1080 and A2058 human tumor cells number[1].
References	[1]. A Melchiori, et al. Inhibition of tumor cell invasion by a highly conserved peptide sequence from the matrix metalloproteinase enzyme prosegment. Cancer Res. 1992 Apr 15;52(8):2353-6. [2]. P P Lee, et al. Functional role of matrix metalloproteinases (MMPs) in mammary epithelial cell development. J Cell Physiol. 2001 Jul;188(1):75-88.

Molecular Formula	C₆₂H₁₀₇N₂₃O₂₀S₂
Molecular Weight	1558.79

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.