Top Suppliers:I want be here


1334177-81-9

1334177-81-9 structure
1334177-81-9 structure
  • Name: S-Acetyl-PEG8-OH
  • Chemical Name: S-acetyl-PEG8 alcohol
  • CAS Number: 1334177-81-9
  • Molecular Formula: C18H36O9S
  • Molecular Weight: 428.538
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-23 05:28:57
  • Modify Date: 2024-01-08 18:47:57
  • S-Acetyl-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name S-acetyl-PEG8 alcohol
Synonyms MFCD13185027
Ethanethioic acid, S-(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl) ester
S-(23-Hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl) ethanethioate
Description S-Acetyl-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 512.3±50.0 °C at 760 mmHg
Molecular Formula C18H36O9S
Molecular Weight 428.538
Flash Point 263.6±30.1 °C
Exact Mass 428.208008
LogP -2.13
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.478
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.