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1334286-77-9

1334286-77-9 structure
1334286-77-9 structure
  • Name: Hydroxy-PEG2-acid
  • Chemical Name: 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid
  • CAS Number: 1334286-77-9
  • Molecular Formula: C7H14O5
  • Molecular Weight: 178.18306
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-10-15 23:11:36
  • Modify Date: 2024-01-03 10:10:46
  • Hydroxy-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid
Synonyms MFCD20646030
Description Hydroxy-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C7H14O5
Molecular Weight 178.18306