1345681-71-1

1345681-71-1 structure
1345681-71-1 structure
  • Name: Amino-PEG12-alcohol
  • Chemical Name: H2N-PEG12-OH
  • CAS Number: 1345681-71-1
  • Molecular Formula: C24H51NO12
  • Molecular Weight: 545.661
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-01 04:05:36
  • Modify Date: 2024-01-02 11:46:53
  • Amino-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name H2N-PEG12-OH
Synonyms 35-Amino-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontan-1-ol
3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontan-1-ol, 35-amino-
Amino-dPEG(R)12-OH
MFCD11041097
Description Amino-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 596.5±45.0 °C at 760 mmHg
Molecular Formula C24H51NO12
Molecular Weight 545.661
Flash Point 314.6±28.7 °C
Exact Mass 545.341125
LogP -4.95
Vapour Pressure 0.0±3.8 mmHg at 25°C
Index of Refraction 1.467