1346502-15-5

1346502-15-5 structure

Name: Br-PEG3-CH2COOH
Chemical Name: Br-PEG3-CH2CO2H
CAS Number: 1346502-15-5
Molecular Formula: C₈H₁₅BrO₅
Molecular Weight: 271.11
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-11-30 22:34:42
Modify Date: 2026-07-15 18:58:34
Br-PEG3-CH2COOH (compound 28) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Name	Br-PEG3-CH2CO2H

Description	Br-PEG3-CH2COOH (compound 28) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Zha Z, et al. Multidentate (18)F-polypegylated styrylpyridines as imaging agents for Aβ plaques in cerebral amyloid angiopathy (CAA). J Med Chem. 2011 Dec 8;54(23):8085-98.