1351556-81-4

1351556-81-4 structure

Name: Propargyl-PEG8-OH
Chemical Name: Propargyl-PEG9-alcohol
CAS Number: 1351556-81-4
Molecular Formula: C₁₉H₃₆O₉
Molecular Weight: 408.484
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2019-01-14 15:37:03
Modify Date: 2024-01-12 10:08:44
Propargyl-PEG8-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	Propargyl-PEG9-alcohol
Synonyms	MFCD27635157 3,6,9,12,15,18,21,24-Octaoxaheptacos-26-yn-1-ol

Description	Propargyl-PEG8-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Goswami LN, et al. Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery. Org Biomol Chem. 2013 Feb 21;11(7):1116-26.