1351556-81-4

1351556-81-4 structure
1351556-81-4 structure
  • Name: Propargyl-PEG8-OH
  • Chemical Name: Propargyl-PEG9-alcohol
  • CAS Number: 1351556-81-4
  • Molecular Formula: C19H36O9
  • Molecular Weight: 408.484
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2019-01-14 15:37:03
  • Modify Date: 2024-01-12 10:08:44
  • Propargyl-PEG8-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name Propargyl-PEG9-alcohol
Synonyms MFCD27635157
3,6,9,12,15,18,21,24-Octaoxaheptacos-26-yn-1-ol
Description Propargyl-PEG8-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Goswami LN, et al. Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery. Org Biomol Chem. 2013 Feb 21;11(7):1116-26.

Density 1.1±0.1 g/cm3
Boiling Point 483.5±40.0 °C at 760 mmHg
Molecular Formula C19H36O9
Molecular Weight 408.484
Flash Point 246.2±27.3 °C
Exact Mass 408.235931
LogP -2.76
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.465