1355197-95-3
1355197-95-3 structure
- Name: Propargyl-PEG6-Boc
- Chemical Name: Propargyl-PEG6-t-butyl ester
- CAS Number: 1355197-95-3
- Molecular Formula: C20H36O8
- Molecular Weight: 404.495
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-11-14 06:38:37
- Modify Date: 2024-01-09 12:28:29
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Propargyl-PEG6-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
| Name | Propargyl-PEG6-t-butyl ester |
|---|---|
| Synonyms |
4,7,10,13,16,19-Hexaoxadocos-21-yn-1-oic acid, 1,1-dimethylethyl ester
MFCD28950777 2-Methyl-2-propanyl 4,7,10,13,16,19-hexaoxadocos-21-yn-1-oate |
| Description | Propargyl-PEG6-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
[1]. Noah Bell, et al. Compounds and methods for inhibiting phosphate transport. WO2012054110A2. |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 458.4±40.0 °C at 760 mmHg |
| Molecular Formula | C20H36O8 |
| Molecular Weight | 404.495 |
| Flash Point | 194.1±27.4 °C |
| Exact Mass | 404.241028 |
| LogP | 0.17 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.458 |