1391728-01-0

1391728-01-0 structure

Name: Propargyl-PEG3-1-o-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite
Chemical Name: Propargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite
CAS Number: 1391728-01-0
Molecular Formula: C₁₆H₂₉N₂O₄P
Molecular Weight: 344.39
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-18 02:32:27
Modify Date: 2024-01-23 11:05:37
Propargyl-PEG3-1-o-b-cyanoethyl-NN-diisopropylphosphoramidite is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Propargyl-PEG3-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite
Synonyms	MFCD28142480

Description	Propargyl-PEG3-1-o-b-cyanoethyl-NN-diisopropylphosphoramidite is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₆H₂₉N₂O₄P
Molecular Weight	344.39