Top Suppliers:I want be here


1415800-38-2

1415800-38-2 structure
1415800-38-2 structure
  • Name: Bromo-PEG5-Boc
  • Chemical Name: Bromo-PEG5-t-butyl ester
  • CAS Number: 1415800-38-2
  • Molecular Formula: C17H33BrO7
  • Molecular Weight: 429.344
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-11-14 12:04:54
  • Modify Date: 2024-01-16 19:24:52
  • Bromo-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bromo-PEG5-t-butyl ester
Synonyms MFCD22683304
2-Methyl-2-propanyl 1-bromo-3,6,9,12,15-pentaoxaoctadecan-18-oate
3,6,9,12,15-Pentaoxaoctadecan-18-oic acid, 1-bromo-, 1,1-dimethylethyl ester
Description Bromo-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Boiling Point 453.9±40.0 °C at 760 mmHg
Molecular Formula C17H33BrO7
Molecular Weight 429.344
Flash Point 228.3±27.3 °C
Exact Mass 428.140961
LogP 0.96
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.466
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.