1415800-41-7

1415800-41-7 structure

Name: Azide-PEG5-Boc
Chemical Name: Azide-PEG5-t-butyl ester
CAS Number: 1415800-41-7
Molecular Formula: C₁₇H₃₃N₃O₇
Molecular Weight: 391.460
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-11-14 20:32:56
Modify Date: 2024-01-23 21:51:13
Azide-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azide-PEG5-t-butyl ester
Synonyms	2-Methyl-2-propanyl 1-azido-3,6,9,12,15-pentaoxaoctadecan-18-oate 3,6,9,12,15-Pentaoxaoctadecan-18-oic acid, 1-azido-, 1,1-dimethylethyl ester MFCD22683303

Description	Azide-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562