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173459-90-0

173459-90-0 structure
173459-90-0 structure
  • Name: PEG4-sulfonic acid
  • Chemical Name: Hydroxy-PEG3-sulfonic acid
  • CAS Number: 173459-90-0
  • Molecular Formula: C8H18O7S
  • Molecular Weight: 258.289
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-15 10:17:36
  • Modify Date: 2025-08-27 00:36:49
  • PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Hydroxy-PEG3-sulfonic acid
Synonyms Ethanesulfonic acid, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-
2-{2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy}ethanesulfonic acid
MFCD29042364
Description PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.3±0.1 g/cm3
Molecular Formula C8H18O7S
Molecular Weight 258.289
Exact Mass 258.077332
LogP -3.31
Index of Refraction 1.486
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