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1802908-05-9

1802908-05-9 structure
1802908-05-9 structure
  • Name: Methyltetrazine-PEG4-amine HCl
  • Chemical Name: Methyltetrazine-PEG4-Amine
  • CAS Number: 1802908-05-9
  • Molecular Formula: C17H25N5O4
  • Molecular Weight: 363.411
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-14 22:54:36
  • Modify Date: 2024-01-02 17:58:11
  • Methyltetrazine-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Methyltetrazine-PEG4-Amine
Synonyms 2-[2-(2-{2-[4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy}ethoxy)ethoxy]ethanamine
Ethanamine, 2-[2-[2-[2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy]ethoxy]ethoxy]-
MFCD28334553
Description Methyltetrazine-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Boiling Point 558.7±60.0 °C at 760 mmHg
Molecular Formula C17H25N5O4
Molecular Weight 363.411
Flash Point 291.7±32.9 °C
Exact Mass 363.190643
LogP -0.73
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.539