1807503-87-2

1807503-87-2 structure
1807503-87-2 structure
  • Name: Methylamino-PEG2-acid HCl
  • Chemical Name: Methylamino-PEG2-acid
  • CAS Number: 1807503-87-2
  • Molecular Formula: C8H17NO4
  • Molecular Weight: 191.225
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-10 09:14:00
  • Modify Date: 2025-09-12 14:57:49
  • Methylamino-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Methylamino-PEG2-acid
Synonyms MFCD28155205
Propanoic acid, 3-[2-[2-(methylamino)ethoxy]ethoxy]-
3-{2-[2-(Methylamino)ethoxy]ethoxy}propanoic acid
Description Methylamino-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 310.2±27.0 °C at 760 mmHg
Molecular Formula C8H17NO4
Molecular Weight 191.225
Flash Point 141.4±23.7 °C
Exact Mass 191.115753
LogP -0.90
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.453
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