Name | Dde Biotin-PEG4-DBCO |
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Synonyms |
1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[19-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-15-(4,4-dimethyl-2,6-dioxocyclohexylidene)-19-oxo-3,6,9,12-tetraoxa-16-azanonadec-1-yl]hexahydro-2-oxo-, (3aS,4S,6aR)-
MFCD28505548 N-[19-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-15-(4,4-dimethyl-2,6-dioxocyclohexylidene)-19-oxo-3,6,9,12-tetraoxa-16-azanonadec-1-yl]-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide |
Description | Dde Biotin-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 1103.9±65.0 °C at 760 mmHg |
Molecular Formula | C47H61N5O9S |
Molecular Weight | 872.080 |
Flash Point | 621.4±34.3 °C |
Exact Mass | 871.419006 |
LogP | 3.80 |
Vapour Pressure | 0.0±0.3 mmHg at 25°C |
Index of Refraction | 1.620 |
Storage condition | -20°C |