Name | Azido-PEG1-NHS ester |
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Synonyms |
1-{[3-(2-Azidoethoxy)propanoyl]oxy}-2,5-pyrrolidinedione
2,5-Pyrrolidinedione, 1-[3-(2-azidoethoxy)-1-oxopropoxy]- MFCD26793773 |
Description | Azido-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
PEGs Alkyl/ether |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Molecular Formula | C9H12N4O5 |
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Molecular Weight | 256.215 |
Exact Mass | 256.080780 |
LogP | -1.51 |