1864003-57-5

1864003-57-5 structure

Name: (+)-Biotin-SLC
Chemical Name: Biotin-SLC
CAS Number: 1864003-57-5
Molecular Formula: C₂₃H₄₁N₃O₄S
Molecular Weight: 427.601
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-14 08:57:19
Modify Date: 2024-01-10 12:39:41
(+)-Biotin-SLC is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Biotin-SLC
Synonyms	MFCD09952651 11-({5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)undecanoic acid Undecanoic acid, 11-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-

Description	(+)-Biotin-SLC is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl-Chain
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.