1864003-57-5

1864003-57-5 structure
1864003-57-5 structure
  • Name: (+)-Biotin-SLC
  • Chemical Name: Biotin-SLC
  • CAS Number: 1864003-57-5
  • Molecular Formula: C23H41N3O4S
  • Molecular Weight: 427.601
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-14 08:57:19
  • Modify Date: 2024-01-10 12:39:41
  • (+)-Biotin-SLC is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Biotin-SLC
Synonyms MFCD09952651
11-({5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)undecanoic acid
Undecanoic acid, 11-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-
Description (+)-Biotin-SLC is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.1±0.1 g/cm3
Boiling Point 730.4±45.0 °C at 760 mmHg
Molecular Formula C23H41N3O4S
Molecular Weight 427.601
Flash Point 395.5±28.7 °C
Exact Mass 427.250488
LogP 2.56
Vapour Pressure 0.0±5.1 mmHg at 25°C
Index of Refraction 1.519