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1924596-31-5

1924596-31-5 structure
1924596-31-5 structure
  • Name: Mal-amido-PEG8-TFP ester
  • Chemical Name: Mal-amido-PEG8-TFP ester
  • CAS Number: 1924596-31-5
  • Molecular Formula: C32H44F4N2O13
  • Molecular Weight: 740.69
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-12 00:54:45
  • Modify Date: 2024-01-14 17:25:55
  • Mal-amido-PEG8-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-amido-PEG8-TFP ester
Synonyms MAL-AMIDO-PEG8-TFP ESTER
Description Mal-amido-PEG8-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C32H44F4N2O13
Molecular Weight 740.69