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2055042-66-3

2055042-66-3 structure
2055042-66-3 structure
  • Name: Hydroxy-PEG9-Boc
  • Chemical Name: Hydroxy-PEG9-t-butyl ester
  • CAS Number: 2055042-66-3
  • Molecular Formula: C25H50O12
  • Molecular Weight: 542.66
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2019-01-01 18:31:01
  • Modify Date: 2024-01-09 17:44:27
  • Hydroxy-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Hydroxy-PEG9-t-butyl ester
Synonyms MFCD30182029
Description Hydroxy-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C25H50O12
Molecular Weight 542.66
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