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252378-66-8

252378-66-8 structure
252378-66-8 structure
  • Name: t-Boc-Aminooxy-PEG3-alcohol
  • Chemical Name: t-Boc-Aminoxy-PEG3-alcohol
  • CAS Number: 252378-66-8
  • Molecular Formula: C11H23NO6
  • Molecular Weight: 265.303
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-10 10:15:16
  • Modify Date: 2024-01-10 13:17:16
  • t-Boc-Aminooxy-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name t-Boc-Aminoxy-PEG3-alcohol
Synonyms 2-Methyl-2-propanyl {2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}carbamate
MFCD24468447
Carbamic acid, N-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
Description t-Boc-Aminooxy-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Molecular Formula C11H23NO6
Molecular Weight 265.303
Exact Mass 265.152527
LogP 0.34
Index of Refraction 1.457
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