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518044-35-4

518044-35-4 structure
518044-35-4 structure
  • Name: Mal-PEG3-Boc
  • Chemical Name: Mal-PEG2-t-butyl ester
  • CAS Number: 518044-35-4
  • Molecular Formula: C17H27NO7
  • Molecular Weight: 313.346
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-04 11:44:31
  • Modify Date: 2024-01-10 12:01:52
  • Mal-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-PEG2-t-butyl ester
Synonyms MAL-PEG2-CH2CH2COOTBU
Description Mal-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Boiling Point 428.7±30.0 °C at 760 mmHg
Molecular Formula C17H27NO7
Molecular Weight 313.346
Flash Point 213.1±24.6 °C
Exact Mass 313.152527
LogP 0.96
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.494
Storage condition 2-8°C