565451-13-0

565451-13-0 structure

Name: Raxibacumab
Chemical Name: Raxibacumab
CAS Number: 565451-13-0
Molecular Formula:
Molecular Weight:
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2019-01-17 16:32:10
Modify Date: 2024-01-02 18:19:23
Raxibacumab (ABthrax) is a human IgG1 monoclonal antibody against Bacillus anthracis protective antigen (PA). Raxibacumab blocks the toxin’s deleterious effects by preventing binding of the protective antigen component of the anthrax toxin to its receptors in host cells, thereby blocking the toxin’s deleterious effects. Raxibacumab can be used for anti-anthrax research[1][2].

Name	Raxibacumab

Description	Raxibacumab (ABthrax) is a human IgG1 monoclonal antibody against Bacillus anthracis protective antigen (PA). Raxibacumab blocks the toxin’s deleterious effects by preventing binding of the protective antigen component of the anthrax toxin to its receptors in host cells, thereby blocking the toxin’s deleterious effects. Raxibacumab can be used for anti-anthrax research[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Mazumdar S. Raxibacumab. MAbs.2009 Nov-Dec;1(6):531-8. [2]. Kummerfeldt CE. Raxibacumab: potential role in the treatment of inhalational anthrax. Infect Drug Resist. 2014 Apr 29;7:101-9. [3]. Cui X, et.al. Late treatment with a protective antigen-directed monoclonal antibody improves hemodynamic function and survival in a lethal toxin-infused rat model of anthrax sepsis. J Infect Dis. 2005 Feb 1;191(3):422-34.

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